1. Hypersensitivity Reactions:

• Do not use Bendroflumethiazide if you have a known allergy or hypersensitivity to thiazide diuretics or any of the ingredients in the medication. Hypersensitivity reactions can range from mild rashes to severe anaphylaxis.

2. Electrolyte Imbalance:

• Bendroflumethiazide can cause significant changes in your electrolyte levels, including low potassium (hypokalemia), low sodium (hyponatremia), and low magnesium (hypomagnesemia). Regular monitoring of electrolyte levels is necessary, especially in long-term use.

3. Severe Kidney or Liver Disease:

• Patients with severe kidney or liver disease should avoid using Bendroflumethiazide as it can worsen their condition. It can also cause azotemia (increased nitrogen levels in the blood) and hepatic coma in patients with severe liver disease.

4. Gout:

• Bendroflumethiazide can increase uric acid levels in the blood, potentially leading to gout attacks. Patients with a history of gout should use this medication with caution.

5. Diabetes:

• Thiazide diuretics can affect blood sugar levels. Patients with diabetes should monitor their blood sugar closely while taking Bendroflumethiazide and may need adjustments to their diabetes medications.

6. Pregnancy and Breastfeeding:

• Bendroflumethiazide should be used during pregnancy only if clearly needed and prescribed by a healthcare provider. It can cross the placenta and may affect the fetus. It is not recommended for use while breastfeeding as it can pass into breast milk and may harm a nursing infant.

7. Photosensitivity:

• Bendroflumethiazide can increase your skin's sensitivity to sunlight, leading to a higher risk of sunburn. Use sunscreen and wear protective clothing when exposed to sunlight.

8. Hypotension:

• This medication can cause a significant drop in blood pressure, especially in the initial stages of treatment or when used in combination with other antihypertensive drugs. Patients should be monitored for signs of hypotension, such as dizziness or fainting.

9. Interactions with Other Medications:

• Bendroflumethiazide can interact with several other medications, including other antihypertensives, corticosteroids, lithium, digoxin, and NSAIDs. Inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.

10. Fluid and Electrolyte Depletion:

• Excessive use of Bendroflumethiazide can lead to significant fluid and electrolyte depletion. Patients should be monitored for signs of dehydration and electrolyte imbalance, such as dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscle fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances.

Patients should follow their healthcare provider's instructions and report any unusual symptoms or side effects promptly. Regular follow-up appointments are essential to monitor the medication's effects and adjust the dosage as necessary.

1. Dosage and Administration:

• Take Bendroflumethiazide exactly as prescribed by your healthcare provider.
• The usual starting dose for hypertension (high blood pressure) is 2.5 mg to 5 mg once daily.
• For edema (fluid retention), the typical dose is 5 mg to 10 mg once daily or every other day, as directed by your doctor.
• Swallow the tablet whole with a full glass of water.
• It is best to take Bendroflumethiazide in the morning to avoid nighttime urination.

2. Consistency:

• Take your medication at the same time each day to help remember to take it.
• Do not change your dose or stop taking the medication without consulting your healthcare provider.

3. Missed Dose:

• If you miss a dose, take it as soon as you remember.
• If it is almost time for your next dose, skip the missed dose and take the next dose at the regular time.
• Do not take two doses at the same time to make up for a missed dose.

4. Storage:

• Store Bendroflumethiazide at room temperature, away from light and moisture.
• Keep the medication in its original container and tightly closed.
• Keep out of reach of children and pets.

• Bendroflumethiazide
• Microcrystalline Cellulose: A filler and binder that helps give the tablet its shape and stability.
• Lactose Monohydrate: Another filler that helps with the tablet's form and stability.
• Starch: Used as a binder and disintegrant to help the tablet dissolve properly.
• Magnesium Stearate: A lubricant that prevents the ingredients from sticking to the equipment during manufacturing.
• Silicon Dioxide: An anti-caking agent that helps to prevent clumping.
• Povidone: A binder that helps hold the tablet together.

• Common side effects include increased urination, dizziness, lightheadedness, dehydration, and electrolyte imbalance.
• Contact your healthcare provider if you experience severe side effects such as muscle cramps, weakness, severe dizziness, fainting, irregular heartbeat, or signs of an allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing).

1. What is Bendroflumethiazide used for? Bendroflumethiazide is a thiazide diuretic medication commonly used to treat high blood pressure (hypertension) and fluid retention (edema) associated with conditions such as heart failure, liver cirrhosis, and kidney disorders. It helps reduce excess fluid in the body by increasing urine production, thereby lowering blood pressure and reducing swelling.

2. How should I take Bendroflumethiazide? Bendroflumethiazide should be taken exactly as prescribed by your healthcare provider. It is usually taken once daily, preferably in the morning to avoid frequent urination at night. You can take it with or without food. It's important to follow your doctor's instructions and not to take more or less than the prescribed dose.

3. What are the possible side effects of Bendroflumethiazide? Common side effects of Bendroflumethiazide include dizziness, lightheadedness, dehydration, electrolyte imbalance (such as low potassium or sodium levels), and increased urination. Less common but more serious side effects can include severe dehydration, electrolyte disturbances, muscle cramps, irregular heartbeat, and severe allergic reactions. Contact your healthcare provider if you experience any unusual or severe symptoms.

4. Are there any interactions with other medications? Yes, Bendroflumethiazide can interact with several other medications. Common interactions include other blood pressure medications, corticosteroids, digoxin, lithium, and non-steroidal anti-inflammatory drugs (NSAIDs). These interactions can either increase the risk of side effects or reduce the effectiveness of Bendroflumethiazide. Always inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.

5. Who should not take Bendroflumethiazide? Bendroflumethiazide is not suitable for everyone. People with severe kidney or liver disease, anuria (inability to urinate), or known hypersensitivity to thiazide diuretics should not take this medication. Additionally, it should be used with caution in individuals with conditions such as gout, diabetes, or lupus. Pregnant or breastfeeding women should consult their healthcare provider before using Bendroflumethiazide. Always discuss your medical history with your doctor to determine if this medication is safe for you.